Ariadne Locker · Clinical Study Repository
Study Documents · Version Control · Regulatory Inspection Ready

Your study documents exist.
Finding them shouldn't be the hard part.

Protocol v2.3. The one before the last amendment. In the shared drive. Or was it the inbox? Or the folder someone renamed? Regulatory inspection in 48 hours.

Ariadne Locker is a fully validated electronic data capture and study management platform — built for teams who need more than a legacy EDC but can't afford six months of IT validation. Patient eConsent, block randomisation, multi-site management, and a tamper-evident audit trail that satisfies GCP, 21 CFR Part 11, and regulatory inspection — without writing a single line of code. Data flows in directly from Sculptor.

Open Locker ↗
Patient eConsent Block randomisation 21 CFR Part 11 No coding required Live now

Ingest, organise,
and retrieve.

Locker gives every study document a permanent, versioned home — and makes sure your team can find it when it matters most.

Ingest

Get documents in

  • Upload protocols, amendments, and brochures
  • Receive eCRF data directly from Sculptor
  • Drag-and-drop bulk document upload
  • Auto-tag by document type and version
  • E-sign documents on upload for chain of custody
Organise

Structure your study file

  • Folder hierarchy by study, site, and document type
  • Version control with mandatory change reason
  • Access controls by role and study
  • Full audit trail of every document action
  • Link related documents (protocol ↔ amendment ↔ consent)
Retrieve

Find it instantly

  • Full-text search across all study documents
  • Filter by document type, version, date, status
  • One-click inspection pack generation
  • Share read-only document links with auditors
  • Export complete study file in standard format

Every document, every version,
always findable.

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Secure Document Repository

Store all study documents in one place — protocols, amendments, consent forms, investigator brochures, regulatory correspondence — with role-based access control.

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Version Control

Every document version tracked with upload timestamp, user identity, and mandatory change reason. The right version is always findable; old versions are never deleted.

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Sculptor Integration

Data collected in Ariadne Sculptor flows directly into Locker. eCRF datasets automatically linked to the corresponding study record — no manual transfer.

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E-Signature on Upload

Capture electronic signatures at the point of document upload. Chain of custody established from day one. 21 CFR Part 11 compliant.

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Full-Text Search

Search across document names, metadata, and content. Find what you need in seconds. Filters by study, site, document type, date, and status.

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Inspection Pack Generation

Generate a complete, formatted inspection pack with one click. Documents collated, versioned, and timestamped — ready for regulatory auditors.

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Role-Based Access

Investigators, coordinators, monitors, and sponsors each see only what they should. Study-level and site-level access controls with full audit trail.

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FHIR R4 Export

Export study data in FHIR R4 format. Integrates with downstream regulatory and clinical data systems without custom ETL.

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GCP & 21 CFR Part 11

Built for regulated environments. Audit trail, e-signatures, version control, and access logs satisfy GCP, ICH E6(R2), and 21 CFR Part 11 requirements.

Ready to see Locker
in action?

Book a 30-minute demo and we'll walk through your study document workflow — or open Locker directly and start organising your first study today.

Open Locker ↗

£2,400/yr · up to 5 users · Sculptor + Locker bundle £4,200/yr (save £600)